[Biorelevant] Two Stage Biorelevant Dissolution Kit

Product Informaion:

• Simulate how a drug product behaves when it contacts the stomach fluid (FaSSGF) and then when it is converted into intestinal fluid (FaSSIF)
• Particularly important for basic drugs with a higher solubility at acidic stomach pH compared to higher intestinal pH
• Results will reveal the drug’s tendency to either supersaturate or precipitate
• Results can help formulation development and optimisation
• Download our step-by-step Experiment Guide on the Home page
• Designed for USP 2 dissolution apparatus
• Drug analysis should be carried out by HPLC

This guide uses the Two Stage Biorelevant Dissolution Kit:

• Simulate how a drug product behaves when it contacts the stomach fluid (FaSSGF) and then when the fluid is converted into intestinal fluid (FaSSIF)
• Particularly important for understanding different formulations of basic drugs with a higher solubility at acidic stomach pH compared to higher intestinal pH
• Results will reveal the drug’s tendency to either supersaturate or precipitate from its formulation in gastrointestinal fluids
• Results can help formulation development and optimisation